Implant-Associated Infection Research at The Ottawa Hospital

The IMPACT Program is a translational research initiative, led by Dr. Hesham Abdelbary, based at The Ottawa Hospital focused on improving the prevention, diagnosis, and treatment of implant-associated infections. Using robust in vitro and clinically representative in vivo research models, the program studies bacterial biofilm formation and develops innovative antimicrobial strategies, including bacteriophage therapy and combination antibiotic approaches.

Through interdisciplinary collaboration, evidence-based medicine, and clinical trial development, the IMPACT Program is working to establish a nationally and internationally recognized Centre of Excellence dedicated to improving patient outcomes.

The IMPACT Program bridges laboratory research and clinical care by translating discoveries in biofilm biology and bacteriophage science into practical therapeutic strategies. By integrating fundamental research, preclinical models, and early-phase clinical trials, the program aims to accelerate the development of safe, effective, and personalized treatments for implant-associated infections.

Mission
‍To use robust in vitro and in vivo research models to develop innovative strategies for the prevention, diagnosis, and treatment of implant-associated infections.

Vision
To develop a Centre of Excellence at The Ottawa Hospital that is nationally and internationally recognized for managing implant-associated infections through innovative translational research and evidence-based medicine.